Fat fuels the flame: triglyceride-rich lipoproteins and arterial inflammation.
نویسنده
چکیده
Recent reviews duly recite the prevailing concept of the mechanisms of atherogenesis.1–5 According to this model, a surfeit of low-density lipoproteins (LDL) favors accumulation and retention of these particles in the arterial intima. There, LDL undergoes oxidative modification. Lipid mediators derived from this oxidized LDL stoke the inflammation now widely deemed a critical culprit in the formation and complication of atheroma.6
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عنوان ژورنال:
- Circulation research
دوره 100 3 شماره
صفحات -
تاریخ انتشار 2007